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Calcium AKG and Cell Health

Here at Xandro Lab, we’ve talked all about calcium AKG longevity benefits (you’ll find links to those throughout this post) but today we want to touch on AKG and cell health, and calcium AKG’s role in cell production.

Calcium AKG Supplement Anti-Aging Benefits

Further Reading: Calcium AKG for Longevity

Alpha-ketoglutarate, otherwise known as AKG, is a molecule used in cellular energy and protein synthesis. It’s used in the Krebs cycle/TCA cycle, which is a series of reactions that occur in the mitochondria, where nearly all our living cells (all cells that use oxygen) produce energy.

In particular:

• It helps form amino acids like glutamine and arginine.
• It regulates how our cells use carbon and nitrogen, preventing overload in our bodies.
• AKG is an antioxidative agent, playing an important role in oxidation reactions, potentially benefiting memory, attention, seizures, coma and those with neurological diseases.

Further Reading: Learn more about Calcium AKG’s benefits on our bones, liver and brain!

• It prevents tumour growth by inducing hypoxia.
• It regulates gene expression and cell signalling pathways related to growth and aging.
• It is used in suberate and redox metabolism, amino acid synthesis, nitrogen transport and immune regulation.
• It impacts protein metabolism, synthesis and absorption.
• It suppresses chronic inflammation to improve frailty, hair loss, body weight and longevity.

Further Reading: Calcium AKG and weight management

• It may activate mTOR signalling pathways, a major regulator of growth in humans.
• It may inhibit autophagy.
• It may prevent muscle protein breakdown.

Further Reading: Are you an athlete looking to improve your recovery? Learn about the Calcium AKG health benefits on muscle recovery.

• It may increase levels of alkaline phosphate, type-I collagen, osteopontin and osteocalcin in certain cells.
• It benefits cardiac cells during surgery, having cardioprotective effects.

Further Reading: Learn more about the benefits of Calcium AKG on heart health!

• It may regulate signalling pathways to oncogenesis, making it a potential anticancer agent by reversing the metabolic response to hypoxia and restoring oxidation in cancer cells.

Let’s keep in mind that AKG has a short life and needs to be connected with another molecule to help its transport into the body, which is where calcium AKG comes in.

End Note

So, does AKG reverse aging? While there is no single supplement that can give you a long life, Ca-AKG has many scientifically-backed studies showing its benefits on longevity. Naturally, alpha ketoglutarate food sources include fish, meat and dairy, with the body also producing AKG when it metabolises various amino acids, such as glutamate.