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All About STACs + FAQs Jump there now: What are Sirtuins Foods? What are the Activators of Sirtuins? Other Potential STACs Does Exercise Activate Sirtuins? End Note Sirtuin activating compounds, otherwise known as STACs are chemicals that activate sirtuin enzymes. Boosting sirtuin activity may help treat diseases, help with weight loss and slow aging. Research on STACs is growing, with …