Blogs

Dr. David Silver's Pitch for LYSOVETA™ as a Cognition Enhancer

Aging is inevitable, but what if there were systems in the body designed to help prevent cognitive decline? The human brain has a natural mechanism to repair its cells and maintain healthy function as we age, thanks to a special compound called LPC-omega-3.

Understanding the Problem

As we age, normal brain metabolism produces reactive oxygen species — unstable molecules that can damage cells. This oxidative damage is a major contributor to brain aging. Neurons, which are critical for memory and cognition, contain large amounts of omega-3 fatty acids like DHA (docosahexaenoic acid), essential for brain health. These fatty acids, however, are highly susceptible to damage. Over time, the levels of DHA in the brain decline, especially in conditions like Alzheimer's disease.

Since the brain can't produce omega-3 fatty acids on its own, it needs to obtain them from the bloodstream. But there's a challenge: the blood-brain barrier (BBB), a protective shield around the brain, prevents most substances from entering, making it hard for regular omega-3 supplements to reach where they're needed most.

The Key Discovery: LPC-omega-3 and the MFSD2A Transporter

Researchers discovered that during brain development, the brain needs a significant supply of omega-3 fatty acids, which coincides with the formation of the blood-brain barrier. This led to the discovery of MFSD2A, a special transport protein that allows LPC-DHA (a form of omega-3 attached to a molecule called lysophosphatidylcholine) to pass through the blood-brain barrier.

Here's why this is important:

• MFSD2A is the primary pathway by which the brain gets DHA, the essential omega-3 fatty acid needed for brain health.
• LPC-DHA, unlike other forms of DHA, is directly transported into the brain by MFSD2A, making it the most bioavailable source of omega-3 for the brain.
• LPCs act as critical building blocks for neuron membranes and are required for proper brain development and function.

Why LYSOVETA™?

With age, the levels of MFSD2A in the brain decrease, limiting the brain's access to essential LPC-DHA. This decline may contribute to cognitive issues as we get older. LYSOVETA™ Aker Biomarine addresses this problem by providing LPC-omega-3, the natural form of omega-3 that is most effectively transported into the brain.

Unlike standard omega-3 supplements that can't easily cross the blood-brain barrier, LYSOVETA™ delivers the exact form of omega-3 the brain uses to repair its membranes. This helps replace damaged neuronal membranes and supports brain function, potentially enhancing cognition and slowing down age-related cognitive decline.

Xandro LPC Neuro: A New Approach to Brain Health

As we age, concerns about cognitive decline — like memory loss, reduced focus and overall brain slowdown — become more common. Xandro LPC Neuro, powered by the breakthrough ingredient LYSOVETA™, is a revolutionary supplement designed to tackle these issues head-on by delivering essential nutrients directly to the brain, supporting its health and longevity.

Unlike traditional omega-3 supplements, LPC Neuro isn't just another fish oil pill. It features LPC-bound DHA and EPA from krill oil, which are designed to cross the blood-brain barrier.

Xandro LPC Neuro is rigorously tested to ensure purity, free from heavy metals and contaminants. It offers a safe and effective way to support your brain's health with the highest quality ingredients. This innovative formula was developed in collaboration with leading researchers, including Dr. David Silver from Duke-NUS Medical School, whose work has emphasised the crucial role of the MFSD2A protein in brain health.

In a Nutshell

• Aging and Brain Health: The brain suffers oxidative damage with age, leading to cognitive decline.
• LPC-omega-3: The body’s natural mechanism for transporting essential omega-3 into the brain to support neuron repair.
• LYSOVETA™: A unique LYSOVETA™ supplement providing the most bioavailable form of omega-3, targeting the root cause of cognitive decline by restoring damaged brain cells.
• Xandro LPC Neuro: You can give your brain the best possible support for maintaining sharpness, focus and overall cognitive wellness as you age with LPC Neuro.